Wednesday, March 20, 2019

Antibiotic Usage Essay -- Biology, DNA

This optimism has been dissipated long before the 20th century when the proliferation of antibiotic drug confrontation bacteria became evident as Fleming predicted earlier. With the rapid development of infected disease associated with antibiotic resistance forced us to change the course we view disease and the way we treat patients. However, antibiotic use has not been without consequence and several factors had contributed to the development of resistance. Some resistances atomic number 18 due to off-the-cuff mutation and these mutations are for select antibiotic resistance whilst other bacteria tend to steal the deoxyribonucleic acid (DNA) from their counterparts who are already familiar with antibiotics (Mims, 2004 Tenover, 2006). antibiotic drug remained effective against most bacterial infection, however these bacterial cells develop resistance and continue to divide resulting in a resistant population and about are no longer effective against infectious disease tha t was killed some years ago (Levy, 2000). The impact of antibiotic resistance could lead to to a greater extent infectious diseases that are hard to treat and could result in a global threat making it difficult as mutation and evolutionary pressure cause increase in antibiotic resistance (Strelkauskas et al, 2010). Antibiotics are extremely important medicine but unfortunately bacteria scram resistant make it problematic as antibiotic resistance had represent problem around the world people continued to travel and youthful technology and sociology exacerbated the development of resistant strains, these strains are transferred from infected people make a repeat in cycle as they moved from whizz place to the next (WHO, 2001). Increased globalisation is responsible for resistance, in macro overpopulat... ...odified penicillin binding proteins. Some resistant bacteria could be dangerous for employment MRSA and the vancomycin resistant staph auerus that are virulent in me rciful pathogens (Strelkauskas, 2010) by reducing the permeability of their membranes as a way of belongings out antibiotic by turning off production of porin and other proteins (Weston, 2008), for example the multi-drug resistant mycobacterium tuberculosis. In pathogens such as Escherichia coli and staphylococcus aureus, efflux pumps played a major role in multi-drug resistance likewise Klebsiella species becoming resistance and other bacteria producing enzymes from Extended Spectrum beta-lactamase (Livermore and Hawley, 2005 Tenover, 2006) also multi-drug resistance antibiotics Acinetobacter Baumanii and the New Delhi Metallo-1(NDM-1) causing havoc amongst the healthcare picture (HPA, 2010).

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